Bhattarai M, Salih M, Regmi M, et al
Randomised clinical trial: Design of the SYNERGY-NASH phase 2b trial to evaluate tirzepatide as a treatment for metabolic dysfunction-associated steatohepatitis and modification of screening strategy to reduce screen failures
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While these side effects are typically dose-related and often fade over time, they remain the leading reason for early drop-out from clinical trials
It contains the active ingredient semaglutide, which can cause side effects such as gastrointestinal disruption